Thursday 26 March 2015

Ostranil Gel –A Remarkable Product


What is the benefit of Ostranil Gel over any other commercially available pain management gel? Ostranil gel is a herbal product manufactured by Salveo Life Sciences for relieving pain. It is indicated for Osteo and Rheumatoid Arthritis, Musculoskeletal pain and Peripheral neuralgia.

Generally all pain relieving gels available commercially contain Diclofenac diethylamine which has an analgesic effect and reduces pain by inhibiting COX2 (Cyclo oxygenase enzyme). The main side-effect of this compound is the gradual destruction of gastric epithelium or gastric corrosion. The inhibition of COX2 enzyme decreases the prostaglandins in the epithelium of the stomach, making it more sensitive to corrosion by gastric acid. These gel chemically also produce methyl salicylate by esterification of salicylic acid with methanol. Chemically synthesized methyl salicylate may have adverse effect on stomach and kidney.

Ostranil gel has anti-inflammatory and imunomodulatory action due to the beneficial action of herb Boswellia serrata (Shallaki). The principle ingredients of this herb are Boswellic acids.

Boswellic acids enhance the catabolism of GAG (glycosaminoglycan) and exhibits a powerful anti-inflammatory and anti arthritic activity.GAG is the principal macromolecule of the extracellular matrix , it aids in repair and regeneration of articular cartilage. Gandhpura oil is the natural source Methyl salicylate   and produces rubefacient action that causes dilation of the capillaries and increases blood circulation. In addition Eucalyptus also has an analgesic and anti-neuralgic action and a rich source of antioxidants that supplies free radicals.

There is no contraindication for use of this gel and just a gram of gel is enough to give relief in acute pain.



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